| Anti-Chlamydia
pneumoniae-IgG, IGA, IgM-Immunoblot Here you see an IgG-Blot scanned with the AID-BlotScanning System
Chlamydia pneumoniae Cut off: Standard setting: |
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The following bands are
characterized:
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| Specificity: There are very strong cross-reactions between antibodies against C. trachomatis and C. pneumoniae (Antibodies against C. trachomatis cause a strong reaction in C. pneumoniae), especially in the low molecular weight region. The 48 kD and 54 kD proteins do however seem to be specific to C. pneumoniae. |
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| Comments:
The popular rate of contamination with C. pneumoniae is very high. One can therefore always expect a reaction from persistent antibodies (IgG) in the immunoblot (LPS, weak MOMP or other bands which are not characterized and whose significance is at the moment uncertain. |
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| Interpretation: IgG: The positive IgG results are uncertain if 2 characterised bands are marked. The IgG results are positive if 3 or more characterised bands are marked. IgM/ IgA: The results are positive if at least 2 characterised bands are marked. Further assistance in interpretation: IgA antibodies against C. pneumoniae appear in cases of chronic pneumonia. According to literature, antibodies against 54 kD, an unidentified band at 40 kD and 60 kD (HSP), point to a higher risk of arterial sclerosis. |
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AID
GmbH Ebinger Strasse 4 D-72479 Straßberg |
