| Anti-Chlamydia
trachomatis-IgG und IgA-Immunoblot zur Diagnostik reaktiver Arthritiden Here you see an anti-Chlamydia trachomatis-IgG-immunoblot, scanned with the AID BlotScanning System
Chlamydia trachomatis Cut off: Standard setting:
Freely adjustable as required. Antigen: Elementary bodies, purified. The following bands are characterised:
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| Specificity: The following bands are considered to be species- specific: MOMP 1 (40 kD), MOMP 1‘ (38 kD), 45 kD, 29 kD, 80 kD and 57 kD. |
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| Comments:
Antibodies against C. trachomatis react very strongly with C. pneumoniae. Antibodies against C. pneumoniae do, however, appear weakly in the C. trachomatis immunoblot (usually due to a weak reaction of the MOMP 1), so that a single weak MOMP 1 band should be ignored, as it suggests a cross-reaction. MOMP 1‘ appears almost exclusively in correlation with MOMP 1 ( very rarely alone). This test kit is intended for use in diagnosing reactive arthritis and chronic diseases according to AMG. |
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| Interpretation: IgG: The positive results are uncertain if one characterised band is detected with one clearly marked MOMP 1 band (intensity > 35 %). The results are positive if two characterised bands are detected with one clearly marked MOMP 1 band (intensity > 35 %). IgA: The positive results are uncertain if only MOMP 1 is clearly marked (intensity >35 %). The results are positive if 1 characterised band is detected together with one clearly marked MOMP 1 band (intensity > 35 %). Further assistance in interpretation: Heat shock proteins (HSP) are significant for chronic infections. Antibodies against HSP 60 are associated with chronic infertility and primary abortions. Cases of reactive arthritis induced by C. trachomatis are often connected with the appearance of antibodies against 57 kD. IgA antibodies also play an important role in this. |
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AID
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