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Human Genetics

HEMATHOLOGY

RDB2210 CVD Panel

Cardiovascular diseases are known to be supported by genetic predisposition. Polymorphisms of several genes are found to rise risk for thrombosis. Detection of some of this polymorphisms is routine in clinical chemistry meanwhile. AID CVD Panel combines the detection of the 6 most important risk alleles on one hybridization strip.

AID CVD Panel enables detection of the following cardiovascular risk alleles:

FV:Q506 Leiden in factor V gene
G20210A in factor II gene
C677T and A1298C in MTHFR gene
-675 4G/5G and -844 A/G in promoter region of PAI-1 gene

 

 

Characteristics

  • Characterization of the most important CVD risk alleles
  • Differentiation between homozygous and heterozygous genotype
  • PCR with subsequent lineprobe assay
  • Specimen: human DNA isolated from buccal swab, Citrate- or EDTA-blood or biopsy
  • Control bands on every strip show correct DNA isolation, amplification and hybridization
  • Results within 4 hours
  • Suited for automated systems
  • Evaluation and documentation with AID Scanning system

 

Reader Systems

AID Scanner