Lactose intolerance is the inability for individuals to digest lactose, the sugar contained in milk products. Due to deficient or reduced activity of enzyme lactase-phlorizin hydrolase there is no breakdown of lactose. Reason therefor is a polymorphism in the enhancer region of the gene for the enzyme. Bacterial fermentation of the lactose is the cause of symptoms like abdominal bloating, cramps, flatulence, diarrhea, nausea and vomiting.
AID Lactose-Intolerance Kit enables detection of polymorphism
G/A -22018 C/T -13910 in the enhancer region of the enzyme lactase-phlorizin hydrolase.
- Detection of the Lactose intolerance allele
- Differentiation between homozygous and heterozygous genotype
- PCR with subsequent lineprobe assay
- Specimen: human DNA isolated from buccal swab, Citrate- or EDTA-blood or biopsy
- Control bands on every strip show correct DNA isolation, amplification and hybridization
- Results within 4 hours
- Suited for automated systems
- Evaluation and documentation with AID Scanning system