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SARS-CoV-2 T cell response

AID CoV-iSpot SARS-CoV-2 FluoroSpot assay – Detects T cell reaction on singular cell level against SARS-CoV-2

AID CoV-iSpot SARS-CoV-2 FluoroSpot Assay

The EliSpot Assay (Enzyme-linked Immuno-Spot Assay) is able to detect a T cell reaction on a singular cell level, and therfore characterizes the individual immune answer of infected persons. The FluoroSpot Assay is an advancement thereof and able to detect polyfunctional T cells.

The evidence of cytokine secretion of T cells - which were stimulated with specific corona virus antigenes - adds up to a highly differentiated picture of the immune response, to monitor the developing course of disease and the immunity after the infection.

The AID CoV-iSpot detects the IFN-γ and IL-2 reaction of specifically activated T cells against coronaviridae (PAN-Corona peptide-mix) and /or SARS-CoV-2 (SARS-CoV-2 peptide-mix).

Also available as AID CoV-iSpot pure, for parallel testing of 24 instead of 12 patients, without PAN-Corona peptide-mix.

Characteristics

  • Detection of a IFN-γ and IL-2 reaction specifically against SARS-CoV-2 and /or other coronaviridae
  • Detection of functional T cells
  • in comparison to antibody tests, where titers are shown to be dropping relatively fast, the T cell reaction is longer lasting
  • Art.no.: ELSP 7010